Is it possible that there is one single medication that has already been developed that can be a treatment for not only leukemia, but Parkinson’s and Alzheimer’s disease as well? Researchers at Georgetown University Medical Center are hopeful that nilotinib fits the bill. Now approved to use in people that have one kind of leukemia, a small trial is creating great excitement in its promising results to clear the brain of toxic proteins.
Georgetown’s medical director of the translational neurotherapeutics program, Fernando Pagan, explains it this way: “Our drug goes into the cells to turn on that garbage disposal mechanism. And if we’re able to degrade these proteins, we could potentially stop the progression of this disorder.”
Due to the encouraging results of the small trial, a larger, more in-depth trial involving 75 patients with Parkinson’s and 42 patients with Alzheimer’s disease is underway. We hope these results will be equally as positive, but regardless, the many years of research that have gone into testing nilotinib as well as other new prospective developments are helping pave the way towards feasible treatment options, or perhaps an eventual cure.
Mice trials have demonstrated some encouraging results, with Parkinson’s mice actually being cured. It’s also proven effective in a small number of human trials in individuals with Parkinson’s and dementia, for which there currently isn’t a treatment designed to stop or even slow the advancement of the diseases. Improvements in many areas were noted for the patients in the initial testing phase, but improvements in speech and mobility were most the pronounced.
Patients with either Parkinson’s or Alzheimer’s are currently being enrolled for the next phase of the study, which is anticipated to be completed in about a year. More details about the upcoming Alzheimer’s study are available here, and information regarding the Parkinson’s study is available here.
For additional resources on assisting individuals with Parkinson’s or Alzheimer’s disease, ask the Texas home care experts at Heaven at Home Senior Care. We are able to provide a wide range of expert in-home care with our fully trained and experienced specialized Alzheimer’s and Parkinson’s caregivers. Contact us at (940) 432-5670 to schedule a free in-home assessment or to allow us to answer any questions you may have.